Ready to take your endurance to the next level? An eight-week study revealed that Siberian ginseng (Eleutherococcus senticosus) could be your secret weapon! Recreational athletes who took 800 mg daily saw a 23% boost in endurance, a 12% increase in VO2 peak, and a higher heart rate during intense exercise. Plus, their bodies burned more fat and saved glycogen, giving them extra energy.

Read more: PubMed

Think Siberian ginseng is just for an energy boost? Think again! This mighty root packs a punch against RNA viruses like human rhinovirus, respiratory syncytial virus, and influenza A. A study revealed that an extract from Eleutherococcus senticosus roots significantly inhibited these viruses' replication in cell cultures. While it didn't affect DNA viruses such as adenovirus and herpes simplex, its antiviral activity stayed stable during preparation and storage.

Read more: PubMed

Imagine tackling type 2 diabetes with a natural powerhouse—Siberian ginseng! In a fascinating study, patients who took this herb for three months saw impressive drops in fasting and postprandial blood sugar levels, HbA1c, total cholesterol, and triglycerides. Unlike the placebo or Panax ginseng, Siberian ginseng also eased symptoms of peripheral neuropathy. Thanks to its unique eleutherosides, this herb might fine-tune glucose metabolism and improve nerve health, all without side effects.

Read more: IJCN

Curious how Siberian ginseng stacks up against type 2 diabetes? Researchers tested a cell-cultured extract on diabetic mice and found it boosts liver antioxidative defenses, cuts down on oxidative stress, and keeps cell membranes flexible. This study shows Siberian ginseng might be a great ally in managing diabetes.

Read more: PMC

Move over, ordinary ginseng—Acanthopanax senticosus, or Siberian Ginseng, is stepping up as a potential cancer fighter! Traditionally known for its anti-fatigue, anti-inflammatory, and cardiovascular benefits, this herb is now making waves for its anticancer properties. Recent studies have shown that it can inhibit the growth of lung and liver tumors, making it a promising candidate for future cancer treatments.

Read more: PubMed

In a fun twist on fighting fatigue, a study found that Siberian ginseng (Acanthopanax senticosus) can seriously boost your stamina! After dosing up some mice, researchers saw that the ginseng's special compounds, particularly eleutheroside E, helped them swim longer and handle sleep deprivation like champs. This root seems to work by using fat for energy, reducing muscle lactic acid, and protecting muscles overall.

Read more: PubMed

Ginsenosides, the active components in ginseng, are multi-tasking heroes for brain health! They target the Akt/CREB/BDNF pathway, crucial in combating neurodegenerative diseases by reducing oxidative stress, inflammation, and cell death. This makes them promising for neuroprotection and potentially slowing disease progression. Researchers are also exploring novel delivery systems to boost these benefits even further.

Read more: ScienceDirect

A study on Acanthopanax senticosus HARMS (ASH), or Siberian ginseng, found that it helps reduce anxiety by balancing autonomic nervous function and boosting brain-derived neurotrophic factor (BDNF) in the hippocampus. In other words, ASH keeps your nervous system chill and your brain happy, making it a potential superstar for mental health.

Read more: PMC

Siberian ginseng might just be a brain booster! A study found that its extracts protect against neuritic atrophy—a key issue in Alzheimer’s disease. Specifically, eleutheroside B, eleutheroside E, and isofraxidin were shown to help maintain the health of neurons affected by amyloid beta in rat cortical neurons. These compounds aid in the regeneration of neurites and synapses, potentially improving memory and cognitive function.

Read more: Springer

Forget the myth that only the young can learn new tricks—Siberian ginseng is here to help aged brains stay sharp! In a study, eleutheroside B and E, compounds from this amazing root, were shown to boost learning and memory in aged rats. Rats treated with these compounds performed better in memory tests and had healthier hippocampal neurons. The magic? Enhanced acetylcholine levels in the brain, crucial for learning and memory.

Read more: PMC

A 2019 study explored the memory-enhancing effects of Eleutherococcus senticosus (Siberian ginseng) leaf extract in mice. After 17 days of oral administration, the extract significantly improved object recognition memory. Key compounds absorbed in the brain and blood were ciwujianoside C3, eleutheroside M, and ciwujianoside B. These compounds, when administered separately, also enhanced memory and showed dendrite extension activity, suggesting their role in improving cognitive function. The findings highlight the potential of E. senticosus leaf extract for memory enhancement.

Read more: PMC

In a study involving 50 healthy women, consuming Siberian ginseng significantly reduced lower limb swelling within hours. This herb works its magic by boosting lymphatic function, specifically through the activation of the Tie2 receptor on lymphatic endothelial cells. This stabilizes lymphatic vessels and improves fluid balance.

Read more: ScienceDirect

Siberian ginseng (Eleutherococcus senticosus) might just be a bone's best friend! A study explored its effects on preventing bone loss in an osteoporosis rat model. Female rats treated with ginseng bark extract had significantly higher bone mineral density after eight weeks compared to untreated rats. Plus, it did all this without messing with body or organ weights or hormone levels. Looks like Siberian ginseng might be a natural way to keep those bones strong!

Read more: MDPI

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Siberian Ginseng Studies (Fun Summaries)